Henry Jayasena (born July 6, 1931 in Bendiyamulla, Gampaha) is a Sri Lankan actor and dramatist.

Jayasena studied at the Gampaha branch of Lorenz College and at Nalanda College, Colombo. He began his career as an Assistant Teacher of English at the Dehipe Primary School in Padiyapellela in the Nuwara Eliya district in 1950 where he directed his first play, Janaki. Jaysena left this post a few months later after passing the General Clerical Service Examination and securing a job with the Public Works Department (PWD) of Sri Lanka.

While with PWD, Jaysena created many of his most famous plays, Janelaya (1962), Thavath Udesenak (1964), Manaranjana Wedawarjana (1965), Ahas Malilga (1966), Hunuwataye Kathawa (1967), Apata Puthey Magak Nethey (1968), Diriya Mawa (1972), Makara (1973) and Sarana Siyoth Se Puthini Habha Yana (1975). Before retiring from government work, he also served as Deputy Director for the National Youth Services Council (Arts and Sports Division) and the Sri Lanka Rupavahini Corporation (Programmes Division).

Also during this time Jaysena was a reputed film actor. An early role was in Sri 296 (1959). During the 1960s Jaysena played the starring roles of Piyal in Gamperaliya (1964), Azdak in Hunuwataye Kathawa (1967) and Lalith in Dahasak Sithuvili (1968).